It's from the 1933 jungle melodrama "White Woman," and the image conjured up thoughts of a similar image somewhere. Yesterday, I found it -- from a slightly more famous film issued the same year, not at Paramount but next door at RKO:
Yep, Fay Wray in "King Kong." (Hey, both she and Carole were romantically involved with writer Robert Riskin; Fay even married him.)
Then again, if the Lombard picture was from a sci-fi/horror film, what would her character be retreating from? A giant ape, a la Kong? Has she been shrunk to a miniature size, put on some mad scientist's table and is now trying to avoid a poke from his pencil? (It could be a scene from the 1940 Paramount film "Dr. Cyclops," although had Carole been in it, her salary would have dwarfed the rest of the cast, pardon the pun. Here's a publicity still from that pic, with Janice Logan, one of the scaled-down victims, in an oversized chair.)
If you can think up a scenario for that Lombard photo, we'd love to hear it.